Campbellsville kept it close for a half, but the Lady Eagles were outscored 12-3 in the third quarter and 14-9 in the fourth frame to fall at Russell County 60-40 on Thursday night.
Senior Danielle Morris led Campbellsville (0-7) with 18 points, including 12-13 from the free-throw line, while freshman Tiffany Slone had 10 points.
Bronte Karr had five rebounds for CHS and Morris three assists.
Russell County (4-1) was led by the 12-point night from eighth-grader Leeann Grider while sophomore Blair Hoover had 11 and junior Kim Pierce 10.